abstract：:Pulmonary endodermal tumor resembling fetal lung describes an uncommon neoplasm of the lung which also has been referred to as pulmonary blastoma and adenocarcinoma of fetal lung type. We describe five cases which fall within a narrow band on the spectrum of pulmonary neoplasms with both epithelial and mesenchymal fea...

journal_title：Human pathology

authors： Nakatani Y,Dickersin GR,Mark EJ

更新日期：1990-11-01 00:00:00

abstract：:In a prior study we reported that monotypic immunoglobulin expression significantly correlated with an increased risk of dissemination by small lymphocytic infiltrates (SLIs) of the orbit and conjunctiva. However, less than half of all monotypic SLIs disseminated. In this study, we applied a large panel of monoclonal ...

journal_title：Human pathology

authors： Medeiros LJ,Harris NL

更新日期：1990-11-01 00:00:00

abstract：:Increasing differentiation in the human endometrium is associated with an apparent decrease in intercellular contacts between endometrial stromal cells ...

journal_title：Human pathology

authors： Parmley TH,Roberts DK,Emsa NJ,Horbelt DV

更新日期：1990-10-01 00:00:00

abstract：:A case of metastatic malignant melanoma simulating a giant cell tumor of bone is reported. This case typifies the diversity of expression of malignant melanoma. Osteoclast-like giant cells were present only in the femoral head metastasis and were not present in the primary lesion. The giant cell component may be refle...

journal_title：Human pathology

authors： Daroca PJ Jr,Reed RJ,Martin PC

更新日期：1990-09-01 00:00:00

abstract：:A renal biopsy of a 57-year-old man with nephrotic syndrome revealed marked glomerular deposition of Congo red-positive, bire-fringent material characteristic for amyloid. Ultrastructurally, however, this material is composed of nonbranching, haphazardly arranged fibrils of approximately three times the thickness of t...

journal_title：Human pathology

authors： Yoshikawa Y,Truong LD,Mattioli C,Cartwright J Jr

更新日期：1990-08-01 00:00:00

abstract：:Endomyocardial biopsies from right, left, or both ventricles were performed in 13 angiographically documented cases of endomyocardial fibrosis. The endocardium was appreciably thickened due to acellular hyalinized collagen tissue in all cases. Variable amounts of elastic tissue intimately admixed with fibrous tissue w...

journal_title：Human pathology

authors： Chopra P,Narula J,Talwar KK,Kumar V,Bhatia ML

更新日期：1990-06-01 00:00:00

abstract：:Clinicopathologic records and neuropathologic tissues of 109 patients who underwent necropsy after treatment with bone marrow transplantation (BMT) were examined. Underlying disorders included leukemia (70), aplastic anemia (25), solid tumors (7), lymphoma (5), Hodgkin's disease (1) and Wiskott-Aldrich syndrome (1). T...

journal_title：Human pathology

authors： Mohrmann RL,Mah V,Vinters HV

更新日期：1990-06-01 00:00:00

abstract：:The use of interleukin-2 (IL-2), either alone or in combination with lymphokine-activated killer cells, tumor infiltrating lymphocytes, or other immunotherapeutic agents has added a new list of alternatives to conventional antineoplastic regimens. Little information is available about the pathologic changes occurring ...

journal_title：Human pathology

authors： Kragel AH,Travis WD,Feinberg L,Pittaluga S,Striker LM,Roberts WC,Lotze MT,Yang JJ,Rosenberg SA

更新日期：1990-05-01 00:00:00

abstract：:Surfactant-associated (SA) glycoproteins are lung-specific proteins produced in the human lung by alveolar type II cells and Clara cells. The distribution of these proteins was studied immunohistochemically in lung tissue obtained postmortem from 12 stillborn fetuses and 49 infants with hyaline membrane disease (HMD)....

journal_title：Human pathology

authors： Margraf LR,Paciga JE,Balis JU

更新日期：1990-04-01 00:00:00

abstract：:To investigate the possibility of human immunodeficiency virus-(HIV) 1 infection of liver cells, liver samples from 17 patients with either acquired immunodeficiency syndrome (AIDS, 13), AIDS-related complex (ARC, 3), or lymphadenopathy syndrome (LAS, 1) were studied. A monoclonal antibody directed against the p24 gag...

journal_title：Human pathology

authors： Housset C,Boucher O,Girard PM,Leibowitch J,Saimot AG,Bréchot C,Marche C

更新日期：1990-04-01 00:00:00

abstract：:Two patients with systemic capillary leak syndrome (SCLS) were followed up clinically for 5 and 2 years, respectively. Muscle biopsy was performed 1 week after the end of an acute crisis in one patient, and after 3 years in the other. In both cases, muscle capillary basement membranes were extremely thick--more than 1...

journal_title：Human pathology

authors： Navarro C,García-Bragado F,Lima J,Fernández JM

更新日期：1990-03-01 00:00:00

abstract：:All cases of primary breast carcinoma seen at the George Washington University Medical Center between 1971 and 1975 and between 1981 and 1986 were reviewed, and examples of pure and mixed infiltrating cribriform carcinoma (ICC) were identified. The relative frequency of ICC did not change significantly from the earlie...

journal_title：Human pathology

authors： Venable JG,Schwartz AM,Silverberg SG

更新日期：1990-03-01 00:00:00

abstract：:A unique case of primary papillary hyperplasia of the gallbladder and cystic and common bile ducts occurring in a young female without calculi, ulcerative colitis, or primary sclerosing cholangitis is reported. The papillary lesion involved the mucosa of the entire gallbladder and of the cystic and common bile ducts. ...

journal_title：Human pathology

authors： Albores-Saavedra J,Defortuna SM,Smothermon WE

更新日期：1990-02-01 00:00:00

abstract：:Autopsy rates continue to decline despite abundant evidence of the autopsy's value. Such an extraordinary contradiction requires that we look beyond issues of education to consider our basic moral and political commitments; to consider, in other words, the kind of society in which we live, and the kind of people we ar...

journal_title：Human pathology

authors： Vance RP

更新日期：1990-02-01 00:00:00

abstract：:The ontogeny and distribution of the epidermal growth factor (EGF) receptor and lipocortin-1, a major cellular substrate of the EGF receptor, were evaluated in a developmental series of fetal and neonatal human lungs (8 to 41 weeks' gestation and stillborn to 16 days' postnatal age). The peroxidase anti-peroxidase tec...

journal_title：Human pathology

authors： Johnson MD,Gray ME,Carpenter G,Pepinsky RB,Stahlman MT

更新日期：1990-02-01 00:00:00

abstract：:A 3-year-old boy with congenital nemaline myopathy had generalized muscle weakness and hypotonia since birth. He developed cardiac symptoms at 2 years of age and died from congestive heart failure. At autopsy, the heart was markedly dilated, involving both ventricles. Rod bodies were recognized not only in skeletal mu...

journal_title：Human pathology

authors： Ishibashi-Ueda H,Imakita M,Yutani C,Takahashi S,Yazawa K,Kamiya T,Nonaka I

更新日期：1990-01-01 00:00:00

abstract：:A mixed gangliocytoma-adenoma occurring in the pituitary fossa of a patient who presented with acromegaly, galactorrhea, and headaches is described. Immunohistochemical studies demonstrated the gangliocytic portion of the tumor to be composed nearly entirely of ganglion cells enmeshed in their neuritic processes and d...

journal_title：Human pathology

authors： Kamel OW,Horoupian DS,Silverberg GD

更新日期：1989-12-01 00:00:00

abstract：:The expression of the proteins encoded by the ras, myc, and erb B-2 oncogenes was examined in 63 paraffin-embedded human cholangiocarcinomas of Thai and English origin using immunohistochemistry. The observed distributions were compared with oncogene expression in a series of human hepatocellular carcinomas. In an att...

journal_title：Human pathology

authors： Voravud N,Foster CS,Gilbertson JA,Sikora K,Waxman J

更新日期：1989-12-01 00:00:00

abstract：:Four human fetuses with the limb body wall malformation complex, also known as the amniotic band syndrome, were examined. Besides malformations of the body wall and the limb(s), anomalies of the internal organs were found in three fetuses, suggesting a disturbance of normal morphogenesis before the fifth week of devel...

journal_title：Human pathology

authors： Hartwig NG,Vermeij-Keers C,De Vries HE,Kagie M,Kragt H

更新日期：1989-11-01 00:00:00

abstract：:Four monoclonal antibodies (MoAbs), 60.15, 61.3, 105.10, and 2.16, directed to different proteins of Mycobacterium tuberculosis were used by an indirect avidin-biotin complex peroxidase-antiperoxidase method to detect mycobacterial antigens in lung, lymph node, and joint tissue specimens of tuberculous patients. Using...

journal_title：Human pathology

authors： Barbolini G,Bisetti A,Colizzi V,Damiani G,Migaldi M,Vismara D

更新日期：1989-11-01 00:00:00

abstract：:A series of 36 cases of chondromyxoid fibroma (CMF) of bone, a rare benign tumor that may be confused with chondrosarcoma, is presented to aid in correctly identifying and diagnosing these neoplasms. In this series, CMFs were found in patients of all age groups, with no predominance between sexes. Long bone tumors wer...

journal_title：Human pathology

authors： Zillmer DA,Dorfman HD

更新日期：1989-10-01 00:00:00

abstract：:Calcitonin and calcitonin gene-related peptide (CGRP) have been localized immunohistochemically in neuroendocrine cells of normal and diseased human lungs. Cells immunoreactive for calcitonin and CGRP first appeared in immature bronchi in the 27th gestational week. Thereafter, both peptides were found in the same bron...

journal_title：Human pathology

authors： Tsutsumi Y

更新日期：1989-09-01 00:00:00

abstract：:The cerebrum, cerebellum, and choroid plexuses from 16 patients with systemic amyloidosis, and the pituitary glands from 14 of these patients, were investigated histologically and immunohistochemically. Cerebrovascular amyloid (CVA) was found in the leptomeninges and cortices of six patients with systemic amyloidosis,...

journal_title：Human pathology

authors： Ishihara T,Nagasawa T,Yokota T,Gondo T,Takahashi M,Uchino F

更新日期：1989-09-01 00:00:00

abstract：:Substantial agreement has previously been demonstrated between qualitative and morphometric grading of gastric dysplasia. In the present study, a further attempt is made to quantitatively define the dysplastic changes in relation to associated benign or malignant changes of gastric mucosa. In total, 232 cases were stu...

journal_title：Human pathology

authors： Tosi P,Baak JP,Luzi P,Miracco C,Lio R,Barbini P

更新日期：1989-09-01 00:00:00

abstract：:Retrovenous perfusion of the myocardium via the coronary sinus and cardiac veins was one of the earliest attempted forms of myocardial revascularization. Although coronary artery revascularization has almost completely replaced venous revascularization as the procedure of choice, the latter approach is still occasiona...

journal_title：Human pathology

authors： Tickman RJ,Gravanis MB,Hunter SB

更新日期：1989-08-01 00:00:00

abstract：:Epithelioid hemangioendotheliomas are uncommon vascular tumors, mainly observed in lung and soft tissues. Liver involvement is infrequent and, in contrast to the extrahepatic localizations of the tumor, has not been subjected to detailed ultrastructural analysis. This prompted us to report the results of the ultrastru...

journal_title：Human pathology

authors： Scoazec JY,Degott C,Reynes M,Benhamou JP,Feldmann G

更新日期：1989-07-01 00:00:00

abstract：:The case of a 65-year-old female patient with a pedunculated left atrial angiosarcoma is presented. Histologically, the tumor was composed of vascular spaces lined by atypical cells with similar cells in the solid portion of the tumor. Immunohistochemical stain for factor VIII-related antigen was positive in the cells...

journal_title：Human pathology

authors： Keohane ME,Lazzam C,Halperin JL,Strauchen JA,Ergin MA

更新日期：1989-06-01 00:00:00

abstract：:Nonalcoholic steatohepatitis (NASH) refers to an alcoholic hepatitis-like histologic pattern found in nonalcoholic patients. A review of 543 liver biopsies diagnosed as alcoholic hepatitis yielded 49 cases of NASH. The patients were commonly middle-aged women who were obese and often diabetic. NASH was usually discove...

journal_title：Human pathology

authors： Lee RG

更新日期：1989-06-01 00:00:00

abstract：:A case of an epithelial-lined (true) adrenal cyst is reported. Although over 300 adrenal cysts have been reported in the literature, true cysts are rare. In this case, a 4.0 cm cyst lined by cuboidal to flattened cells with bland cytologic features was incidentally found at autopsy. Immunologic studies performed on fo...

journal_title：Human pathology

authors： Medeiros LJ,Weiss LM,Vickery AL Jr

更新日期：1989-05-01 00:00:00

abstract：:Rhabdomyomas are rare tumors that usually arise within the heart, orocervical, or vulvovaginal regions. The cardiac tumors have a characteristic immature morphology, occur often in association with tuberous sclerosis, and are regarded as hamartomas rather than true neoplasms. The histogenesis of the extracardiac tumor...

journal_title：Human pathology

authors： Zwick DL,Livingston K,Clapp L,Kosnik E,Yates A

更新日期：1989-04-01 00:00:00

abstract：:Neoglycoproteins are readily available conjugates of a histochemically inert carrier protein and histochemically crucial carbohydrate moieties which are covalently attached to the carrier protein by chemical synthesis. Biotinylation renders these conjugates detectable in formalin-fixed, paraffin-embedded tissue sectio...

journal_title：Human pathology

authors： Kayser K,Gabius HJ,Ciesiolka T,Ebert W,Bach S

更新日期：1989-04-01 00:00:00

abstract：:We have begun a systematic study of human papillomavirus (HPV) infection in colposcopically and/or morphologically normal epithelium of the uterine cervix. Paired biopsies were taken from the lesions (cervical intraepithelial neoplasia [CIN], condyloma, invasive carcinoma) and from the normal-appearing adjacent epithe...

journal_title：Human pathology

authors： Colgan TJ,Percy ME,Suri M,Shier RM,Andrews DF,Lickrish GM

更新日期：1989-04-01 00:00:00

abstract：:The pertinent clinical data and histologic features of the testes in 57 autopsied acquired immunodeficiency syndrome (AIDS) patients were analyzed and compared with those of 55 age-matched control patients without AIDS. The testes of the AIDS patients showed a significantly lower degree of spermatogenesis (determined ...

journal_title：Human pathology

authors： De Paepe ME,Waxman M

更新日期：1989-03-01 00:00:00

abstract：:Twenty-six women with multiple human papillomavirus (HPV)-related lesions of the lower genital tract were investigated by immunohistochemistry for the internal genus-specific capsid antigen of HPV and by DNA-DNA in situ hybridization with 35S-radiolabeled probes for sequences of HPV-6/11, HPV-16, and HPV-18. The vulva...

journal_title：Human pathology

authors： Pilotti S,Gupta J,Stefanon B,De Palo G,Shah KV,Rilke F

更新日期：1989-02-01 00:00:00

abstract：:We studied the histopathologic, immunohistochemical, and ultrastructural features of the extracellular matrix (ECM) in 20 immunologically defined large-cell lymphomas, including immunoblastic sarcoma of B cells (three patients), peripheral T cell lymphoma (five patients), large non-cleaved follicular center cell (FCC)...

journal_title：Human pathology

authors： McCurley TL,Gay RE,Gay S,Glick AD,Jones MR,Haralson MA,Collins RD

更新日期：1989-02-01 00:00:00

abstract：:Cytochrome P-450 specific for steroid 17 alpha-hydroxylation (P-45017 alpha) was immunolocalized in normal and hyperfunctioning adrenal glands of pigs, bovines, and humans, using a specific IgG fraction raised against the enzyme. P-45017 alpha was present in the zona fasciculata (ZF) and zona reticularis (ZR), but not...

journal_title：Human pathology

authors： Sasano H,Mason JI,Sasano N

更新日期：1989-02-01 00:00:00

abstract：:Lymphocytic colitis, previously termed "microscopic colitis", is a clinicopathologic syndrome of watery diarrhea, grossly normal colonoscopy, and mucosal inflammatory changes. Since lymphocytic colitis is a new, incompletely characterized entity, a histopathologic study was performed to compare lymphocytic colitis (n ...

journal_title：Human pathology

authors： Lazenby AJ,Yardley JH,Giardiello FM,Jessurun J,Bayless TM

更新日期：1989-01-01 00:00:00

abstract：:We report novel renal histopathologic features in a patient with hemolytic uremic syndrome after allogeneic bone marrow transplantation who survived with plasma exchange therapy. This distribution of vascular lesions within the kidney differed from previously described cases, which were uniformly fatal, in that there ...

journal_title：Human pathology

authors： Arends MJ,Harrison DJ

更新日期：1989-01-01 00:00:00

abstract：:Basal cell hyperplasia (BCH) is an uncommon proliferative lesion of the prostate gland. We studied ten cases of BCH, one case of an unusual adenoid basal cell tumor (ABT), and one case of a prostatic adenoid cystic carcinoma (ACC), using a panel of antibodies to define the histogenesis of these lesions. Monoclonal ant...

journal_title：Human pathology

authors： Grignon DJ,Ro JY,Ordoñez NG,Ayala AG,Cleary KR

更新日期：1988-12-01 00:00:00

abstract：:A 51-year-old man presented with a paratracheal tumor. He had undergone resection of a thyroid tumor 15 years previously; at that time, the histologic diagnosis had been anaplastic carcinoma. When the tumor recurred, the presumptive clinical diagnosis was medullary thyroid carcinoma. Histologic examination revealed a ...

journal_title：Human pathology

authors： Asa SL,Dardick I,Van Nostrand AW,Bailey DJ,Gullane PJ

更新日期：1988-12-01 00:00:00